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| Introductory seminar on nonlinear dynamics of DNA |
| 2017-05-05
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| Institute of Theoretical Physics | | Chinese Academy of Sciences | | Key Laboratory of Theoretical Physics | | Seminar | | Title 题目 | Introductory seminar on nonlinear dynamics of DNA | | Speaker 报告人 | Dr. M. Vanitha | | Affiliation 所在单位 | ITP-CAS | | Date 日期 | 05 May 2017, Friday: 15:45--16:45 | | Venue 地点 | Conference Hall 322, ITP
| | Abstract 摘要 | In this introductory seminar talk, I will summarise my previous research accomplishments on base pair opening in DNA double helical molecule in the form of solitons. Base pair opening in an inhomogenous double helical molecular chain with flexible strands is studied by solving the governing dynamical equations analytically and numerically. The results show that inhomogeneity in stacking and hydrogen bonds in localized and periodic forms and the helicity do not alter the amplitude of the bubble soliton. However the flexibility of the strands makes the amplitude to damp. On the otherhand the velocity of the bubble soliton is unaltered. Further the above effects introduce small fluctuation in the tail of the bubble soliton without affecting the robust nature of the soliton during propagation. Based on this well-established nonlinear dynamical framework to account for DNA denaturation--annealing dynamics, I will briefly discuss our initial effort to understand the dynamics of coordinated neural activity in the observed neural dynamics from place cell recordings from mice, including mouse models that are relevant to autism and mental illness in general. I will conclude my talk with the current topic of my interest on networks. | | Contact person 所内联系人 | Hai-Jun Zhou |
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